FRIH_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: FTH1 , FTH, FTHL6 , OK/SW-cl.84, PIG15
Protein names and data: FRIH_HUMAN , Ferritin heavy chain; Ferritin H subunit; 1.16.3.1 , Cell proliferation-inducing gene 15 protein; Ferritin heavy chain, N-terminally processed Lenght: 183 a.a.
Mass: 21226 Da
fasta formatted sequence

Function: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
Catalytic activity: 4 Fe(2+) + 4 H(+) + O(2) = 4 Fe(3+) + 2 H(2)O.

Database cross-references

UniProt: P02794
Ensembl: ENST00000273550
MIM: 134770
neXtProt: NX_P02794
Antibodypedia: P02794 (may not find the protein thus also not any antibody)
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