FSCN1_HUMAN

Source: hRBCD ; ID: IPI00163187
PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: FSCN1 , FAN1, HSN, SNL
Protein names and data: FSCN1_HUMAN , Fascin , 55 kDa actin-bundling protein; Singed-like protein; p55 Lenght: 493 a.a.
Mass: 54530 Da
fasta formatted sequence
Function: Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.
Cellular location: Cytoplasm, cytoskeleton. Cell projection, filopodium. Cell projection, invadopodium. Cytoplasm, cytosol. Note=In glioma cells, partially colocalizes with F-actin stress fibers in the cytosol.
Tissue specificity: Ubiquitous.

Database cross-references

UniProt: Q16658
Ensembl: ENST00000382361
MIM: 602689
neXtProt: NX_Q16658
Antibodypedia: Q16658 (may not find the protein thus also not any antibody)
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