FUBP2_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: KHSRP , FUBP2
Protein names and data: FUBP2_HUMAN , Far upstream element-binding protein 2; FUSE-binding protein 2 , KH type-splicing regulatory protein; KSRP; p75 Lenght: 711 a.a.
Mass: 73115 Da
fasta formatted sequence
Function: Binds to the dendritic targeting element and may play a role in mRNA trafficking (By similarity). Part of a ternary complex that binds to the downstream control sequence (DCS) of the pre-mRNA. Mediates exon inclusion in transcripts that are subject to tissue-specific alternative splicing. May interact with single- stranded DNA from the far-upstream element (FUSE). May activate gene expression. Also involved in degradation of inherently unstable mRNAs that contain AU-rich elements (AREs) in their 3'- UTR, possibly by recruiting degradation machinery to ARE- containing mRNAs.
Cellular location: Nucleus. Cytoplasm. Note=A small proportion is also found in the cytoplasm of neuronal cell bodies and dendrites (By similarity).
Tissue specificity: Detected in neural and non-neural cell lines.

Database cross-references

UniProt: Q92945
Ensembl: ENST00000398148
MIM: 603445
neXtProt: NX_Q92945
Antibodypedia: Q92945 (may not find the protein thus also not any antibody)
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