FUMH_HUMAN

Source: hRBCD ; ID: IPI00296053
PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: FH
Protein names and data: FUMH_HUMAN , Fumarate hydratase, mitochondrial; Fumarase; 4.2.1.2; Flags: Precursor Lenght: 510 a.a.
Mass: 54637 Da
fasta formatted sequence

Function: Also acts as a tumor suppressor.
Catalytic activity: (S)-malate = fumarate + H(2)O.
Pathway: Carbohydrate metabolism; tricarboxylic acid cycle; (S)- malate from fumarate: step 1/1.
Disease:
Cellular location: Isoform Mitochondrial: Mitochondrion. Isoform Cytoplasmic: Cytoplasm.
Tissue specificity: Expressed in red blood cells; underexpressed in red blood cells (cytoplasm) of patients with hereditary non- spherocytic hemolytic anemia of unknown etiology.

Genetic variants

Database cross-references

UniProt: P07954
Ensembl: ENST00000366560
MIM: 136850
MIM: 150800
MIM: 606812
neXtProt: NX_P07954
Antibodypedia: P07954 (may not find the protein thus also not any antibody)
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