Source: PM19886704
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: GPI
Protein names and data: G6PI_HUMAN , Glucose-6-phosphate isomerase; GPI; , Autocrine motility factor; AMF; Neuroleukin; NLK; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI; Sperm antigen 36; SA-36 Lenght: 558 a.a.
Mass: 63147 Da
fasta formatted sequence

Function: Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons.
Catalytic activity: D-glucose 6-phosphate = D-fructose 6- phosphate.
Pathway: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3- phosphate and glycerone phosphate from D-glucose: step 2/4.
Cellular location: Cytoplasm. Secreted.

Genetic variants

Database cross-references

UniProt: P06744
Ensembl: ENST00000356487
Ensembl: ENST00000415930
MIM: 172400
MIM: 613470
neXtProt: NX_P06744
Antibodypedia: P06744 (may not find the protein thus also not any antibody)
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