GANAB_HUMAN

Source: hRBCD ; ID: IPI00011454
PM19886704
PM23856902
BSc_CH
PM22954596
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)

Gene names: GANAB , G2AN, KIAA0088
Protein names and data: GANAB_HUMAN , Neutral alpha-glucosidase AB; 3.2.1.84 , Alpha-glucosidase 2; Glucosidase II subunit alpha; Flags: Precursor Lenght: 944 a.a.
Mass: 106874 Da
fasta formatted sequence

Function: Cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins.
Catalytic activity: Hydrolysis of terminal (1->3)-alpha-D- glucosidic links in (1->3)-alpha-D-glucans.
Pathway: Glycan metabolism; N-glycan metabolism.
Cellular location: Endoplasmic reticulum (By similarity). Golgi apparatus (By similarity). Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue specificity: Detected in placenta.

Genetic variants

Database cross-references

UniProt: Q14697
Ensembl: ENST00000346178
Ensembl: ENST00000356638
Ensembl: ENST00000526210
Ensembl: ENST00000532402
Ensembl: ENST00000534613
MIM: 104160
neXtProt: NX_Q14697
Antibodypedia: Q14697 (may not find the protein thus also not any antibody)
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