GBRAP_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: GABARAP , FLC3B , HT004
Protein names and data: GBRAP_HUMAN , Gamma-aminobutyric acid receptor-associated protein , GABA(A) receptor-associated protein; MM46; Flags: Precursor Lenght: 117 a.a.
Mass: 13918 Da
fasta formatted sequence
Function: Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
Cellular location: Endomembrane system (By similarity). Cytoplasm, cytoskeleton (By similarity). Golgi apparatus membrane (By similarity). Cytoplasmic vesicle, autophagosome. Note=Largely associated with intracellular membrane structures including the Golgi apparatus and postsynaptic cisternae. Colocalizes with microtubules (By similarity). Localizes also to discrete punctae along the ciliary axoneme (By similarity).
Tissue specificity: Heart, brain, placenta, liver, skeletal muscle, kidney and pancreas.

Database cross-references

UniProt: O95166
Ensembl: ENST00000302386
MIM: 605125
neXtProt: NX_O95166
Antibodypedia: O95166 (may not find the protein thus also not any antibody)
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