GLO2_HUMAN

Source: hRBCD ; ID: IPI00003933
PM19886704
PM23856902
BSc_CH
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: HAGH , GLO2, HAGH1
Protein names and data: GLO2_HUMAN , Hydroxyacylglutathione hydrolase, mitochondrial; 3.1.2.6 , Glyoxalase II; Glx II; Flags: Precursor Lenght: 308 a.a.
Mass: 33806 Da
fasta formatted sequence
Function: Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid.
Catalytic activity: S-(2-hydroxyacyl)glutathione + H(2)O = glutathione + a 2-hydroxy carboxylate.
Pathway: Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 2/2.
Cellular location: Isoform 1: Mitochondrion matrix. Isoform 2: Cytoplasm.
Tissue specificity: Expressed in liver and kidney.

Database cross-references

UniProt: Q16775
Ensembl: ENST00000397353
Ensembl: ENST00000397356
MIM: 138760
neXtProt: NX_Q16775
Antibodypedia: Q16775 (may not find the protein thus also not any antibody)
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