GMPR1_HUMAN

Source: hRBCD ; ID: IPI00304803
PM19886704
PM23856902
PM22954596
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: GMPR , GMPR1
Protein names and data: GMPR1_HUMAN , GMP reductase 1; 1.7.1.7 , Guanosine 5'-monophosphate oxidoreductase 1; Guanosine monophosphate reductase 1 Lenght: 345 a.a.
Mass: 37419 Da
fasta formatted sequence
Function: Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.
Catalytic activity: Inosine 5'-phosphate + NH(3) + NADP(+) = guanosine 5'-phosphate + NADPH.

Genetic variants

At least two different alleles are known.

Database cross-references

UniProt: P36959
Ensembl: ENST00000259727
MIM: 139265
neXtProt: NX_P36959
Antibodypedia: P36959 (may not find the protein thus also not any antibody)
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