Source: hRBCD ; ID: IPI00288947
Marked as 'Membrane associated protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)

Gene names: GNAQ , GAQ
Protein names and data: GNAQ_HUMAN , Guanine nucleotide-binding protein G(q) subunit alpha , Guanine nucleotide-binding protein alpha-q Lenght: 359 a.a.
Mass: 42142 Da
fasta formatted sequence

Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Regulates B-cell selection and survival and is required to prevent B-cell-dependent autoimmunity. Regulates chemotaxis of BM-derived neutrophils and dendritic cells (in vitro) (By similarity).
Cellular location: Nucleus (By similarity). Membrane (By similarity). Nucleus membrane (By similarity). Note=Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes (By similarity).
Tissue specificity: Predominantly expressed in ovary, prostate, testis and colon. Down-regulated in the peripheral blood lymphocytes (PBLs) of rheumatoid arthritis patients (at protein level).

Genetic variants

Database cross-references

UniProt: P50148
Ensembl: ENST00000286548
MIM: 163000
MIM: 185300
MIM: 600998
neXtProt: NX_P50148
Antibodypedia: P50148 (may not find the protein thus also not any antibody)
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