GRAN_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: GCA , GCL
Protein names and data: GRAN_HUMAN , Grancalcin Lenght: 217 a.a.
Mass: 24010 Da
fasta formatted sequence
Function: Calcium-binding protein that may play a role in the adhesion of neutrophils to fibronectin. May play a role in the formation of focal adhesions.
Cellular location: Cytoplasm. Cytoplasmic granule membrane; Peripheral membrane protein; Cytoplasmic side. Note=Primarily cytosolic in the absence of calcium or magnesium ions. Relocates to granules and other membranes in response to elevated calcium and magnesium levels.
Tissue specificity: Detected in neutrophils and macrophages (at protein level). Highly expressed in bone marrow.

Genetic variants

Database cross-references

UniProt: P28676
Ensembl: ENST00000437150
MIM: 607030
neXtProt: NX_P28676
Antibodypedia: P28676 (may not find the protein thus also not any antibody)
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