GRM4_HUMAN

Source: hRBCD ; ID: IPI00442030
PM19886704
PM23856902
Marked as 'Integral membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: GRM4 , GPRC1D, MGLUR4
Protein names and data: GRM4_HUMAN , Metabotropic glutamate receptor 4; mGluR4; Flags: Precursor Lenght: 912 a.a.
Mass: 101868 Da
fasta formatted sequence
Function: G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity.
Cellular location: Cell membrane; Multi-pass membrane protein.
Tissue specificity: Strongly expressed in the cerebellum. Expressed at low levels in hippocampus, hypothalamus and thalamus. No expression detected in liver.

Genetic variants

Database cross-references

UniProt: Q14833
Ensembl: ENST00000374177
Ensembl: ENST00000374181
Ensembl: ENST00000455714
Ensembl: ENST00000535756
Ensembl: ENST00000538487
Ensembl: ENST00000544773
MIM: 604100
neXtProt: NX_Q14833
Antibodypedia: Q14833 (may not find the protein thus also not any antibody)
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