GRP78_HUMAN

Source: hRBCD ; ID: IPI00003362
PM19886704
PM23856902
BSc_CH
PM22954596
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: HSPA5 , GRP78
Protein names and data: GRP78_HUMAN , 78 kDa glucose-regulated protein; GRP-78 , Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78; Heat shock 70 kDa protein 5; Immunoglobulin heavy chain-binding protein; BiP; Flags: Precursor Lenght: 654 a.a.
Mass: 72333 Da
fasta formatted sequence
Function: Probably plays a role in facilitating the assembly of multimeric protein complexes inside the endoplasmic reticulum. Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10, probably to facilitate the release of DNAJC10 from its substrate.
Disease:
Cellular location: Endoplasmic reticulum lumen. Melanosome. Cytoplasm (By similarity). Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Genetic variants

Database cross-references

UniProt: P11021
Ensembl: ENST00000324460
MIM: 138120
neXtProt: NX_P11021
Antibodypedia: P11021 (may not find the protein thus also not any antibody)
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