GSTP1_HUMAN

Source: hRBCD ; ID: IPI00219757
PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: GSTP1 , FAEES3, GST3
Protein names and data: GSTP1_HUMAN , Glutathione S-transferase P; 2.5.1.18 , GST class-pi; GSTP1-1 Lenght: 210 a.a.
Mass: 23356 Da
fasta formatted sequence
Function: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration.
Catalytic activity: RX + glutathione = HX + R-S-glutathione.
Cellular location: Cytoplasm. Mitochondrion. Nucleus. Note=The 83 N-terminal amino-acids function as un uncleaved transit peptide, and arginine residues within it are crucial for motochondrial localization.

Genetic variants

Database cross-references

UniProt: P09211
Ensembl: ENST00000398606
MIM: 134660
neXtProt: NX_P09211
Antibodypedia: P09211 (may not find the protein thus also not any antibody)
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