GUAA_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: GMPS
Protein names and data: GUAA_HUMAN , GMP synthase [glutamine-hydrolyzing]; 6.3.5.2 , GMP synthetase; Glutamine amidotransferase Lenght: 693 a.a.
Mass: 76715 Da
fasta formatted sequence
Function: Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNA synthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division.
Catalytic activity: ATP + XMP + L-glutamine + H(2)O = AMP + diphosphate + GMP + L-glutamate.
Pathway: Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.
Disease:
Cellular location: Cytoplasm.

Database cross-references

UniProt: P49915
Ensembl: ENST00000496455
MIM: 600358
neXtProt: NX_P49915
Antibodypedia: P49915 (may not find the protein thus also not any antibody)
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