H12_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: HIST1H1C , H1F2
Protein names and data: H12_HUMAN , Histone H1.2 , Histone H1c; Histone H1d; Histone H1s-1 Lenght: 213 a.a.
Mass: 21365 Da
fasta formatted sequence
Function: Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
Cellular location: Nucleus. Chromosome. Note=Mainly localizes in euchromatin. Distribution goes in parallel with DNA concentration.

Genetic variants

Database cross-references

UniProt: P16403
Ensembl: ENST00000343677
MIM: 142710
neXtProt: NX_P16403
Antibodypedia: P16403 (may not find the protein thus also not any antibody)
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