H15_HUMAN

Source: BSc_CH
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: HIST1H1B , H1F5
Protein names and data: H15_HUMAN , Histone H1.5 , Histone H1a; Histone H1b; Histone H1s-3 Lenght: 226 a.a.
Mass: 22580 Da
fasta formatted sequence
Function: Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity).
Cellular location: Nucleus. Chromosome. Note=According to PubMed:15911621 more commonly found in heterochromatin. According to PubMed:10997781 associates with actively transcribed chromatin and not heterochromatin.
Tissue specificity: Ubiquitous. Expressed in the majority of the cell lines tested and in testis.

Genetic variants

Database cross-references

UniProt: P16401
Ensembl: ENST00000331442
MIM: 142711
neXtProt: NX_P16401
Antibodypedia: P16401 (may not find the protein thus also not any antibody)
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