Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: HIST1H2AB , H2AFA
Protein names and data: H2A1B_HUMAN , Histone H2A type 1-B/E , Histone H2A.2; Histone H2A/a; Histone H2A/m Lenght: 130 a.a.
Mass: 14135 Da
fasta formatted sequence

Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Cellular location: Nucleus. Chromosome.

Database cross-references

UniProt: P04908
Ensembl: ENST00000259791
Ensembl: ENST00000303910
MIM: 602786
MIM: 602795
neXtProt: NX_P04908
Antibodypedia: P04908 (may not find the protein thus also not any antibody)
Local full text data: click here

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