H2AV_HUMAN

Source: hRBCD ; ID: IPI00018278
PM23856902
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: H2AFV , H2AV
Protein names and data: H2AV_HUMAN , Histone H2A.V , H2A.F/Z Lenght: 128 a.a.
Mass: 13509 Da
fasta formatted sequence
Function: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division (By similarity).
Cellular location: Nucleus (By similarity). Chromosome (By similarity).

Genetic variants

Database cross-references

UniProt: Q71UI9
Ensembl: ENST00000222690
Ensembl: ENST00000308153
Ensembl: ENST00000349299
Ensembl: ENST00000350771
Ensembl: ENST00000381124
neXtProt: NX_Q71UI9
Antibodypedia: Q71UI9 (may not find the protein thus also not any antibody)
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