H2B1C_HUMAN

Source: BSc_CH
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: HIST1H2BC , H2BFK
Protein names and data: H2B1C_HUMAN , Histone H2B type 1-C/E/F/G/I , Histone H2B.1 A; Histone H2B.a; H2B/a; Histone H2B.g; H2B/g; Histone H2B.h; H2B/h; Histone H2B.k; H2B/k; Histone H2B.l; H2B/l Lenght: 126 a.a.
Mass: 13906 Da
fasta formatted sequence
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
Cellular location: Nucleus. Chromosome.

Genetic variants

Database cross-references

UniProt: P62807
Ensembl: ENST00000244601
Ensembl: ENST00000314332
Ensembl: ENST00000356530
Ensembl: ENST00000359985
Ensembl: ENST00000377733
Ensembl: ENST00000396984
MIM: 602798
MIM: 602804
MIM: 602805
MIM: 602807
MIM: 602847
neXtProt: NX_P62807
Antibodypedia: P62807 (may not find the protein thus also not any antibody)
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