H2B1L_HUMAN

Source: PM23856902
BSc_CH
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: HIST1H2BL , H2BFC
Protein names and data: H2B1L_HUMAN , Histone H2B type 1-L , Histone H2B.c; H2B/c Lenght: 126 a.a.
Mass: 13952 Da
fasta formatted sequence
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Cellular location: Nucleus. Chromosome.

Genetic variants

Database cross-references

UniProt: Q99880
Ensembl: ENST00000377401
MIM: 602800
neXtProt: NX_Q99880
Antibodypedia: Q99880 (may not find the protein thus also not any antibody)
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