H2B2E_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: HIST2H2BE , H2BFQ
Protein names and data: H2B2E_HUMAN , Histone H2B type 2-E , Histone H2B-GL105; Histone H2B.q; H2B/q Lenght: 126 a.a.
Mass: 13920 Da
fasta formatted sequence
Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
Cellular location: Nucleus. Chromosome.

Database cross-references

UniProt: Q16778
Ensembl: ENST00000369155
Ensembl: ENST00000583061
MIM: 601831
neXtProt: NX_Q16778
Antibodypedia: Q16778 (may not find the protein thus also not any antibody)
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