Source: hRBCD ; ID: IPI00453473
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)

Gene names: HIST1H4A , H4/O, H4FO
Protein names and data: H4_HUMAN , Histone H4 Lenght: 103 a.a.
Mass: 11367 Da
fasta formatted sequence

Function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Cellular location: Nucleus. Chromosome.

Genetic variants

Database cross-references

UniProt: P62805
Ensembl: ENST00000289352
Ensembl: ENST00000340756
Ensembl: ENST00000354348
Ensembl: ENST00000355057
Ensembl: ENST00000355981
Ensembl: ENST00000357549
Ensembl: ENST00000358064
Ensembl: ENST00000359907
Ensembl: ENST00000360441
Ensembl: ENST00000369157
Ensembl: ENST00000369165
Ensembl: ENST00000377364
Ensembl: ENST00000377727
Ensembl: ENST00000377745
Ensembl: ENST00000377803
Ensembl: ENST00000392932
Ensembl: ENST00000392933
Ensembl: ENST00000392938
Ensembl: ENST00000392939
Ensembl: ENST00000539745
MIM: 142750
MIM: 602822
MIM: 602823
MIM: 602824
MIM: 602825
MIM: 602826
MIM: 602827
MIM: 602828
MIM: 602829
MIM: 602830
MIM: 602831
MIM: 602833
MIM: 615069
neXtProt: NX_P62805
Antibodypedia: P62805 (may not find the protein thus also not any antibody)
Local full text data: click here

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