HMGB1_HUMAN

Source: hRBCD ; ID: IPI00219096
PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: HMGB1 , HMG1
Protein names and data: HMGB1_HUMAN , High mobility group protein B1 , High mobility group protein 1; HMG-1 Lenght: 215 a.a.
Mass: 24894 Da
fasta formatted sequence
Function: DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity).
Cellular location: Nucleus. Chromosome.

Genetic variants

Database cross-references

UniProt: P09429
Ensembl: ENST00000339872
Ensembl: ENST00000341423
Ensembl: ENST00000399494
Ensembl: ENST00000405805
MIM: 163905
neXtProt: NX_P09429
Antibodypedia: P09429 (may not find the protein thus also not any antibody)
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