HNRPC_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: HNRNPC , HNRPC
Protein names and data: HNRPC_HUMAN , Heterogeneous nuclear ribonucleoproteins C1/C2; hnRNP C1/C2 Lenght: 306 a.a.
Mass: 33670 Da
fasta formatted sequence

Function: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.
Cellular location: Nucleus. Note=Component of ribonucleosomes.

Genetic variants

Database cross-references

UniProt: P07910
Ensembl: ENST00000320084
Ensembl: ENST00000420743
Ensembl: ENST00000430246
Ensembl: ENST00000449098
Ensembl: ENST00000553300
Ensembl: ENST00000554455
Ensembl: ENST00000554969
Ensembl: ENST00000555883
Ensembl: ENST00000556628
Ensembl: ENST00000556897
Ensembl: ENST00000557201
MIM: 164020
neXtProt: NX_P07910
Antibodypedia: P07910 (may not find the protein thus also not any antibody)
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