HPBP1_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: HSPBP1 , HSPBP , PP1845
Protein names and data: HPBP1_HUMAN , Hsp70-binding protein 1; HspBP1 , Heat shock protein-binding protein 1; Hsp70-binding protein 2; HspBP2; Hsp70-interacting protein 1; Hsp70-interacting protein 2 Lenght: 362 a.a.
Mass: 39474 Da
fasta formatted sequence

Function: Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.
Tissue specificity: Ubiquitous.

Genetic variants

Database cross-references

UniProt: Q9NZL4
Ensembl: ENST00000255631
Ensembl: ENST00000433386
Ensembl: ENST00000587922
MIM: 612939
neXtProt: NX_Q9NZL4
Antibodypedia: Q9NZL4 (may not find the protein thus also not any antibody)
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