HS90A_HUMAN

Source: hRBCD ; ID: IPI00328602
PM19886704
PM23856902
PM22954596
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: HSP90AA1 , HSP90A, HSPC1, HSPCA
Protein names and data: HS90A_HUMAN , Heat shock protein HSP 90-alpha , Heat shock 86 kDa; HSP 86; HSP86; Renal carcinoma antigen NY-REN-38 Lenght: 732 a.a.
Mass: 84660 Da
fasta formatted sequence
Function: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
Cellular location: Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Database cross-references

UniProt: P07900
Ensembl: ENST00000216281
Ensembl: ENST00000334701
MIM: 140571
neXtProt: NX_P07900
Antibodypedia: P07900 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.