HS90B_HUMAN

Source: hRBCD ; ID: IPI00334775
PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: HSP90AB1 , HSP90B, HSPC2, HSPCB
Protein names and data: HS90B_HUMAN , Heat shock protein HSP 90-beta; HSP 90 , Heat shock 84 kDa; HSP 84; HSP84 Lenght: 724 a.a.
Mass: 83264 Da
fasta formatted sequence
Function: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
Cellular location: Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Genetic variants

Database cross-references

UniProt: P08238
Ensembl: ENST00000353801
Ensembl: ENST00000371554
Ensembl: ENST00000371646
MIM: 140572
neXtProt: NX_P08238
Antibodypedia: P08238 (may not find the protein thus also not any antibody)
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