Source: hRBCD ; ID: IPI00304925
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)

Gene names: HSPA1A , HSPA1, HSX70
Protein names and data: HSP71_HUMAN , Heat shock 70 kDa protein 1A/1B , Heat shock 70 kDa protein 1/2; HSP70-1/HSP70-2; HSP70.1/HSP70.2 Lenght: 641 a.a.
Mass: 70052 Da
fasta formatted sequence

Function: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.
Cellular location: Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Tissue specificity: HSPA1B is testis-specific.

Genetic variants

Database cross-references

UniProt: P08107
Ensembl: ENST00000375650
Ensembl: ENST00000375651
Ensembl: ENST00000391548
Ensembl: ENST00000391555
Ensembl: ENST00000400040
Ensembl: ENST00000430065
Ensembl: ENST00000433487
Ensembl: ENST00000441618
Ensembl: ENST00000445736
Ensembl: ENST00000450744
MIM: 140550
MIM: 603012
neXtProt: NX_P08107
Antibodypedia: P08107 (may not find the protein thus also not any antibody)
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