Source: BSc_CH
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: HYOU1 , GRP170, ORP150
Protein names and data: HYOU1_HUMAN , Hypoxia up-regulated protein 1 , 150 kDa oxygen-regulated protein; ORP-150; 170 kDa glucose-regulated protein; GRP-170; Flags: Precursor Lenght: 999 a.a.
Mass: 111335 Da
fasta formatted sequence

Function: Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding.
Cellular location: Endoplasmic reticulum lumen.
Tissue specificity: Highly expressed in tissues that contain well- developed endoplasmic reticulum and synthesize large amounts of secretory proteins. Highly expressed in liver and pancreas and lower expression in brain and kidney. Also expressed in macrophages within aortic atherosclerotic plaques, and in breast cancers.

Database cross-references

UniProt: Q9Y4L1
Ensembl: ENST00000404233
Ensembl: ENST00000571646
MIM: 601746
neXtProt: NX_Q9Y4L1
Antibodypedia: Q9Y4L1 (may not find the protein thus also not any antibody)
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