HYPK_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: HYPK , C15orf63 , HSPC136
Protein names and data: HYPK_HUMAN , Huntingtin-interacting protein K , Huntingtin yeast partner K Lenght: 129 a.a.
Mass: 14665 Da
fasta formatted sequence

Function: Has a chaperone-like activity preventing polyglutamine (polyQ) aggregation of HTT. Protects against HTT polyQ-mediated apoptosis in Neuro2a neuronal cells. Required for optimal NAA10- NAA15 complex-mediated N-terminal acetylation.
Cellular location: Nucleus. Cytoplasm.

Genetic variants

Database cross-references

UniProt: Q9NX55
Ensembl: ENST00000406925
Ensembl: ENST00000442995
MIM: 612784
neXtProt: NX_Q9NX55
Antibodypedia: Q9NX55 (may not find the protein thus also not any antibody)
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