ICLN_HUMAN

Source: hRBCD ; ID: IPI00004795
PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: CLNS1A , CLCI, ICLN
Protein names and data: ICLN_HUMAN , Methylosome subunit pICln , Chloride channel, nucleotide sensitive 1A; Chloride conductance regulatory protein ICln; I(Cln); Chloride ion current inducer protein; ClCI; Reticulocyte pICln Lenght: 237 a.a.
Mass: 26215 Da
fasta formatted sequence
Function: The interaction with Sm proteins inhibits their assembly on U RNA and interferes with snRNP biogenesis. Inhibits the binding of survival motor neuron protein (SMN) to Sm proteins. May participate in cellular volume control by activation of a swelling-induced chloride conductance pathway.
Cellular location: Cytoplasm. Nucleus. Cytoplasm, cytoskeleton. Note=A small fraction is also associated with the cytoskeleton.

Genetic variants

Database cross-references

UniProt: P54105
Ensembl: ENST00000525428
Ensembl: ENST00000528364
MIM: 602158
neXtProt: NX_P54105
Antibodypedia: P54105 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.