IF4A1_HUMAN

Source: hRBCD ; ID: IPI00025491
PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: EIF4A1 , DDX2A, EIF4A
Protein names and data: IF4A1_HUMAN , Eukaryotic initiation factor 4A-I; eIF-4A-I; eIF4A-I; 3.6.4.13 , ATP-dependent RNA helicase eIF4A-1 Lenght: 406 a.a.
Mass: 46154 Da
fasta formatted sequence
Function: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
Catalytic activity: ATP + H(2)O = ADP + phosphate.

Database cross-references

UniProt: P60842
Ensembl: ENST00000293831
Ensembl: ENST00000577269
MIM: 602641
neXtProt: NX_P60842
Antibodypedia: P60842 (may not find the protein thus also not any antibody)
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