IF4A2_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: EIF4A2 , DDX2B, EIF4F
Protein names and data: IF4A2_HUMAN , Eukaryotic initiation factor 4A-II; eIF-4A-II; eIF4A-II; 3.6.4.13 , ATP-dependent RNA helicase eIF4A-2 Lenght: 407 a.a.
Mass: 46402 Da
fasta formatted sequence
Function: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
Catalytic activity: ATP + H(2)O = ADP + phosphate.

Genetic variants

Database cross-references

UniProt: Q14240
Ensembl: ENST00000323963
Ensembl: ENST00000440191
MIM: 601102
neXtProt: NX_Q14240
Antibodypedia: Q14240 (may not find the protein thus also not any antibody)
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