RBCC Red Blood Cell Collection

IFNG_HUMAN

Source: PM19886704
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: IFNG
Protein names and data: IFNG_HUMAN , Interferon gamma; IFN-gamma , Immune interferon; Flags: Precursor Lenght: 166 a.a.
Mass: 19348 Da
fasta formatted sequence
Function: Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
Disease: ( OMIM: 147570 609135 ) Aplastic anemia (AA) [MIM:609135]: A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements. It is characterized by peripheral pancytopenia and marrow hypoplasia. Note=Disease susceptibility may be associated with variations affecting the gene represented in this entry.
Cellular location: Secreted.
Tissue specificity: Released primarily from activated T lymphocytes.

Genetic variants

29 - 29 K -> Q. VAR_004017
160 - 160 R -> Q. VAR_004018

Database cross-references

UniProt: P01579
Ensembl: ENST00000229135
MIM: 147570
MIM: 609135
neXtProt: NX_P01579
Antibodypedia: P01579 (may not find the protein thus also not any antibody)
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