IQGA1_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: IQGAP1 , KIAA0051
Protein names and data: IQGA1_HUMAN , Ras GTPase-activating-like protein IQGAP1 , p195 Lenght: 1657 a.a.
Mass: 189252 Da
fasta formatted sequence
Function: Binds to activated CDC42 but does not stimulate its GTPase activity. It associates with calmodulin. Could serve as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. May promote neurite outgrowth.
Cellular location: Cell membrane.
Tissue specificity: Expressed in the placenta, lung, and kidney. A lower level expression is seen in the heart, liver, skeletal muscle and pancreas.

Genetic variants

Database cross-references

UniProt: P46940
Ensembl: ENST00000268182
MIM: 603379
neXtProt: NX_P46940
Antibodypedia: P46940 (may not find the protein thus also not any antibody)
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