RBCC Red Blood Cell Collection

ITA1_HUMAN

Source: PM23856902
Marked as 'Integral membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: ITGA1
Protein names and data: ITA1_HUMAN , Integrin alpha-1 , CD49 antigen-like family member A; Laminin and collagen receptor; VLA-1; CD49a; Flags: Precursor Lenght: 1179 a.a.
Mass: 130848 Da
fasta formatted sequence
Function: Integrin alpha-1/beta-1 is a receptor for laminin and collagen. It recognizes the proline-hydroxylated sequence G-F-P-G- E-R in collagen. Involved in anchorage-dependent, negative regulation of EGF-stimulated cell growth.
Cellular location: Membrane; Single-pass type I membrane protein.

Genetic variants

480 - 480 T -> M (in dbSNP:rs4145748). VAR_034022 4145748
670 - 670 V -> I (in dbSNP:rs2279587). VAR_049630 2279587
961 - 961 I -> M (in dbSNP:rs12520591). VAR_034023 12520591
1108 - 1108 E -> G (in dbSNP:rs988574). VAR_034024 988574

Database cross-references

UniProt: P56199
Ensembl: ENST00000282588
MIM: 192968
neXtProt: NX_P56199
Antibodypedia: P56199 (may not find the protein thus also not any antibody)
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