JOS2_HUMAN

Source: PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: JOSD2 , SBBI54
Protein names and data: JOS2_HUMAN , Josephin-2; 3.4.19.12 , Josephin domain-containing protein 2 Lenght: 188 a.a.
Mass: 20756 Da
fasta formatted sequence
Function: Cleaves 'Lys-63'-linked poly-ubiquitin chains, and with lesser efficiency 'Lys-48'-linked poly-ubiquitin chains (in vitro). May act as a deubiquitinating enzyme.
Catalytic activity: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C- terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).
Cellular location: Cytoplasm, cytosol.

Database cross-references

UniProt: Q8TAC2
Ensembl: ENST00000391815
Ensembl: ENST00000595669
Ensembl: ENST00000598418
Ensembl: ENST00000601423
MIM: 615324
neXtProt: NX_Q8TAC2
Antibodypedia: Q8TAC2 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.