KAD6_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: AK6 , CINAP , AD-004, CGI-137
Protein names and data: KAD6_HUMAN , Adenylate kinase isoenzyme 6; AK6; 2.7.4.3 , Adrenal gland protein AD-004; Coilin-interacting nuclear ATPase protein; hCINAP; Dual activity adenylate kinase/ATPase; AK/ATPase Lenght: 172 a.a.
Mass: 20061 Da
fasta formatted sequence
Function: Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. AMP and dAMP are the preferred substrates, but CMP and dCMP are also good substrates. IMP is phosphorylated to a much lesser extent. All nucleoside triphosphates ATP, GTP, UTP, CTP, dATP, dCTP, dGTP, and TTP are accepted as phosphate donors. CTP is the best phosphate donor, followed by UTP, ATP, GTP and dCTP. May have a role in nuclear energy homeostasis. Has also ATPase activity. May be involved in regulation of Cajal body (CB) formation.
Catalytic activity: ATP + AMP = 2 ADP.
Cellular location: Nucleus, nucleoplasm. Nucleus, Cajal body. Note=Displays widespread diffuse nucleoplasmic distribution but not detected in nucleoli. Detected in Cajal bodies but not in all cells.

Database cross-references

UniProt: Q9Y3D8
Ensembl: ENST00000380818
Ensembl: ENST00000380822
Ensembl: ENST00000575603
Ensembl: ENST00000576354
neXtProt: NX_Q9Y3D8
Antibodypedia: Q9Y3D8 (may not find the protein thus also not any antibody)
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