KAP2_HUMAN

Source: PM19886704
PM23856902
Marked as 'Membrane associated protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: PRKAR2A , PKR2, PRKAR2
Protein names and data: KAP2_HUMAN , cAMP-dependent protein kinase type II-alpha regulatory subunit Lenght: 404 a.a.
Mass: 45518 Da
fasta formatted sequence

Function: Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase.
Cellular location: Cytoplasm. Cell membrane. Note=Colocalizes with PJA2 in the cytoplasm and the cell membrane.
Tissue specificity: Four types of regulatory chains are found: I- alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.

Database cross-references

UniProt: P13861
Ensembl: ENST00000265563
Ensembl: ENST00000454963
MIM: 176910
neXtProt: NX_P13861
Antibodypedia: P13861 (may not find the protein thus also not any antibody)
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