KC1A_HUMAN

Source: hRBCD ; ID: IPI00183400
PM19886704
PM23856902
BSc_CH
PM22954596
Marked as 'Non-membrane protein'
Confidence: high (present in two of the MS resources) Search PubMed for
(RBC AND this entry)
Gene names: CSNK1A1
Protein names and data: KC1A_HUMAN , Casein kinase I isoform alpha; CKI-alpha; 2.7.11.1 , CK1 Lenght: 337 a.a.
Mass: 38915 Da
fasta formatted sequence
Function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates CTNNB1 at 'Ser-45'. May play a role in segregating chromosomes during mitosis.
Catalytic activity: ATP + a protein = ADP + a phosphoprotein.
Cellular location: Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Nucleus speckle. Note=Localizes to the centrosome in interphase cells, and to kinetochore fibers during mitosis.

Genetic variants

Database cross-references

UniProt: P48729
Ensembl: ENST00000377843
Ensembl: ENST00000515768
MIM: 600505
neXtProt: NX_P48729
Antibodypedia: P48729 (may not find the protein thus also not any antibody)
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