KCC2G_HUMAN

Source: PM19886704
Marked as 'Integral membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: CAMK2G , CAMK, CAMK-II, CAMKG
Protein names and data: KCC2G_HUMAN , Calcium/calmodulin-dependent protein kinase type II subunit gamma; CaM kinase II subunit gamma; CaMK-II subunit gamma; 2.7.11.17 Lenght: 558 a.a.
Mass: 62609 Da
fasta formatted sequence
Function: Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplsamic reticulum Ca(2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow- twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.
Catalytic activity: ATP + a protein = ADP + a phosphoprotein.
Cellular location: Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side (Probable).
Tissue specificity: Expressed in skeletal muscle.

Genetic variants

Database cross-references

UniProt: Q13555
Ensembl: ENST00000305762
Ensembl: ENST00000322635
Ensembl: ENST00000322680
Ensembl: ENST00000351293
Ensembl: ENST00000394762
Ensembl: ENST00000423381
MIM: 602123
neXtProt: NX_Q13555
Antibodypedia: Q13555 (may not find the protein thus also not any antibody)
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