KCY_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: CMPK1 , CMK, CMPK, UCK, UMK, UMPK
Protein names and data: KCY_HUMAN , UMP-CMP kinase; 2.7.4.14 , Deoxycytidylate kinase; CK; dCMP kinase; Nucleoside-diphosphate kinase; 2.7.4.6; Uridine monophosphate/cytidine monophosphate kinase; UMP/CMP kinase; UMP/CMPK Lenght: 196 a.a.
Mass: 22222 Da
fasta formatted sequence
Function: Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.
Catalytic activity: ATP + (d)CMP = ADP + (d)CDP. ATP + UMP = ADP + UDP. ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
Cellular location: Nucleus. Cytoplasm. Note=Predominantly nuclear.
Tissue specificity: Ubiquitously expressed.

Database cross-references

UniProt: P30085
Ensembl: ENST00000371873
Ensembl: ENST00000450808
MIM: 191710
neXtProt: NX_P30085
Antibodypedia: P30085 (may not find the protein thus also not any antibody)
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