LBP_HUMAN
Source:
PM23856902
Marked as 'Non-membrane protein'
Confidence:
low (only semi-automatic identification from reviews)
Search PubMed for
(RBC AND this entry)
Gene names:
LBP
Protein names and data:
LBP_HUMAN
, Lipopolysaccharide-binding protein; LBP; Flags: Precursor
Lenght: 481 a.a.
Mass: 53384 Da
fasta formatted sequence
Function:
Binds to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and acts as an affinity enhancer for CD14, facilitating its association with LPS.
Cellular location:
Secreted.
Genetic variants
9 - 9
P -> L (in dbSNP:rs2232580). VAR_028243
2232580
111 - 111
R -> Q (in dbSNP:rs2232583). VAR_049737
2232583
125 - 125
L -> I (in dbSNP:rs2232585). VAR_028244
2232585
147 - 147
E -> K (in dbSNP:rs36015492). VAR_049738
36015492
157 - 157
S -> C (in dbSNP:rs2232586). VAR_061293
2232586
166 - 166
V -> M (in dbSNP:rs5744204). VAR_028245
5744204
242 - 242
M -> I (in dbSNP:rs2232601). VAR_028246
2232601
283 - 283
D -> G (in dbSNP:rs2232607). VAR_028247
2232607
294 - 294
H -> R (in dbSNP:rs2232608). VAR_028248
2232608
333 - 333
P -> L (in dbSNP:rs2232613). VAR_028249
2232613
339 - 339
L -> F (in dbSNP:rs5744212). VAR_028250
5744212
364 - 364
I -> T (in dbSNP:rs2232615). VAR_049739
2232615
436 - 436
F -> L (in dbSNP:rs2232618). VAR_028251
2232618
445 - 445
A -> T (in dbSNP:rs2232619). VAR_028252
2232619
Database cross-references
UniProt:
P18428
Ensembl:
ENST00000217407
MIM:
151990
neXtProt:
NX_P18428
Antibodypedia:
P18428
(may not find the protein thus also not any antibody)
Local full text data:
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