LEG9_HUMAN

Source: hRBCD ; ID: IPI00010477
PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: LGALS9
Protein names and data: LEG9_HUMAN , Galectin-9; Gal-9 , Ecalectin; Tumor antigen HOM-HD-21 Lenght: 355 a.a.
Mass: 39518 Da
fasta formatted sequence
Function: Binds galactosides. Has high affinity for the Forssman pentasaccharide. May play a role in thymocyte-epithelial interactions relevant to the biology of the thymus. Inhibits cell proliferation. It is a ligand for HAVCR2/TIM3. Induces T-helper type 1 lymphocyte (Th1) death. Isoform Short acts as an eosinophil chemoattractant.
Cellular location: Cytoplasm (By similarity). Secreted (By similarity). Note=May also be secreted by a non-classical secretory pathway (By similarity).
Tissue specificity: Peripheral blood leukocytes and lymphatic tissues. Overexpressed in Hodgkin disease tissue.

Genetic variants

Database cross-references

UniProt: O00182
Ensembl: ENST00000302228
Ensembl: ENST00000395473
MIM: 601879
neXtProt: NX_O00182
Antibodypedia: O00182 (may not find the protein thus also not any antibody)
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