Source: BSc_CH
Marked as 'Integral membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)

Gene names: LMAN1 , ERGIC53, F5F8D
Protein names and data: LMAN1_HUMAN , Protein ERGIC-53 , ER-Golgi intermediate compartment 53 kDa protein; Gp58; Intracellular mannose-specific lectin MR60; Lectin mannose-binding 1; Flags: Precursor Lenght: 510 a.a.
Mass: 57549 Da
fasta formatted sequence

Function: Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins.
Cellular location: Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein.
Tissue specificity: Ubiquitous.

Genetic variants

Database cross-references

UniProt: P49257
Ensembl: ENST00000251047
MIM: 227300
MIM: 601567
neXtProt: NX_P49257
Antibodypedia: P49257 (may not find the protein thus also not any antibody)
Local full text data: click here

Users' comments

Login to add a comment.