LPHN2_HUMAN

Source: PM23856902
Marked as 'Integral membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)

Gene names: LPHN2 , KIAA0786, LEC1, LPHH1
Protein names and data: LPHN2_HUMAN , Latrophilin-2 , Calcium-independent alpha-latrotoxin receptor 2; CIRL-2; Latrophilin homolog 1; Lectomedin-1; Flags: Precursor Lenght: 1459 a.a.
Mass: 163349 Da
fasta formatted sequence

Function: Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor propably implicated in the regulation of exocytosis (By similarity).
Cellular location: Cell membrane; Multi-pass membrane protein.
Tissue specificity: Expressed very widely in all normal tissues tested. Expression is variable in tumor cell lines, apparently elevated in some lines and absent or markedly reduced in others.

Database cross-references

UniProt: O95490
Ensembl: ENST00000319517
Ensembl: ENST00000335786
Ensembl: ENST00000359929
Ensembl: ENST00000370713
Ensembl: ENST00000370715
Ensembl: ENST00000370717
Ensembl: ENST00000370723
Ensembl: ENST00000370725
Ensembl: ENST00000370728
Ensembl: ENST00000370730
Ensembl: ENST00000394879
MIM: 607018
neXtProt: NX_O95490
Antibodypedia: O95490 (may not find the protein thus also not any antibody)
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