RBCC

M3K6_HUMAN

Source: PM19886704
PM23856902
Marked as 'Non-membrane protein'
Confidence: low (only semi-automatic identification from reviews) Search PubMed for
(RBC AND this entry)
Gene names: MAP3K6 , ASK2, MAPKKK6, MEKK6
Protein names and data: M3K6_HUMAN , Mitogen-activated protein kinase kinase kinase 6; 2.7.11.25 , Apoptosis signal-regulating kinase 2 Lenght: 1288 a.a.
Mass: 142596 Da
fasta formatted sequence
Function: Component of a protein kinase signal transduction cascade. Activates the JNK, but not ERK or p38 kinase pathways.
Catalytic activity: ATP + a protein = ADP + a phosphoprotein.

Genetic variants

455 - 455 T -> I (in dbSNP:rs1138294). VAR_032832 1138294
499 - 499 R -> C (in dbSNP:rs11247641). VAR_046050 11247641
544 - 544 R -> W (in dbSNP:rs55671988). VAR_046051 55671988
622 - 622 N -> K (in dbSNP:rs35659744). VAR_032833 35659744
668 - 668 R -> G (in dbSNP:rs55869163). VAR_046052 55869163
673 - 673 R -> L (in dbSNP:rs56359841). VAR_046053 56359841
869 - 869 P -> T (in a breast cancer sample; somatic mutation). VAR_035629
925 - 925 S -> L (in a breast pleomorphic lobular carcinoma sample; somatic mutation). VAR_046054
968 - 968 T -> I (in an ovarian endometrioid cancer sample; somatic mutation). VAR_046055
969 - 969 S -> N (in dbSNP:rs17856498). VAR_032834 17856498
1061 - 1061 A -> T (in dbSNP:rs55990440). VAR_046056 55990440
1233 - 1233 G -> A (in dbSNP:rs17162549). VAR_046057 17162549

Database cross-references

UniProt: O95382
Ensembl: ENST00000357582
Ensembl: ENST00000374040
Ensembl: ENST00000493901
MIM: 604468
neXtProt: NX_O95382
Antibodypedia: O95382 (may not find the protein thus also not any antibody)
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RBCC Red Blood Cell Collection

M3K6_HUMAN

Genetic variants

Database cross-references

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