MANF_HUMAN

Source: PM23856902
PM22954596
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: MANF , ARMET, ARP
Protein names and data: MANF_HUMAN , Mesencephalic astrocyte-derived neurotrophic factor , Arginine-rich protein; Protein ARMET; Flags: Precursor Lenght: 182 a.a.
Mass: 20700 Da
fasta formatted sequence
Function: Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
Cellular location: Secreted.

Database cross-references

UniProt: P55145
Ensembl: ENST00000528157
Ensembl: ENST00000566546
MIM: 601916
neXtProt: NX_P55145
Antibodypedia: P55145 (may not find the protein thus also not any antibody)
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