MESD_HUMAN

Source: PM23856902
PM22954596
Marked as 'Non-membrane protein'
Confidence: medium (present in either hRBCD or BSc_CH or PM22954596) Search PubMed for
(RBC AND this entry)
Gene names: MESDC2 , KIAA0081, MESD , UNQ1911/PRO4369
Protein names and data: MESD_HUMAN , LDLR chaperone MESD , Mesoderm development candidate 2; Mesoderm development protein; Renal carcinoma antigen NY-REN-61; Flags: Precursor Lenght: 234 a.a.
Mass: 26077 Da
fasta formatted sequence
Function: Chaperone specifically assisting the folding of beta- propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction.
Cellular location: Endoplasmic reticulum.

Database cross-references

UniProt: Q14696
Ensembl: ENST00000261758
Ensembl: ENST00000561312
MIM: 607783
neXtProt: NX_Q14696
Antibodypedia: Q14696 (may not find the protein thus also not any antibody)
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